Fourteen U0126 MAPK inhibitor of 19 patients (74%) received further pelvic external beam radiotherapy (EBRT) alone; five (26%) patients underwent adjuvant hysterectomy. The median follow-up for all patients was 63 months; 60 months for patients treated with adjuvant hysterectomy (range 31-68 months) and 85 months for patients treated with further EBRT. None of the patients treated with adjuvant hysterectomy developed any significant late toxicity. Seven patients (50%) treated with

EBRT have relapsed compared with none in the adjuvant hysterectomy arm (P = 0.068). Six patients (43%) in the EBRT arm have subsequently died of recurrent disease compared with none in the adjuvant hysterectomy arm (P = 0.152).

Conclusions: Adjuvant hysterectomy after unsuccessful ICBT does not seem to increase late toxicity and reduces the Fisk of pelvic recurrence and may improve survival. The role of

adjuvant hysterectomy after suboptimal chemoradiation merits further investigation in clinical trials. (C) 2009 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.”
“The propagation of ultrasonic guided waves in layered viscoelastic film/substrate materials has been investigated. Based on the plane strain theory, a numerical model of the guided waves propagating in thin film on the substrate is developed in the frequency domain by employing the spectral finite element method. The surface normal displacement and the propagating characteristic are obtained and analyzed, which depends not only on the material parameters of the film, but also on those of the substrate. If the substrate velocity is faster

than that OSI-906 mouse of the film, the dispersion takes on the normal, otherwise, the anomalous dispersion will appear, and thin film properties for different film/substrate systems can be identified. The guided wave is attenuated gradually due to energy dissipation caused by material viscosity and rapidly at the location near the source. With the receiver distance increasing, it becomes slower. Clearly models for ultrasonic generation and propagation in layered viscoelastic film/substrate materials must include the effect of viscoelasticity on the dispersive wave. (c) 2010 American Institute ISRIB order of Physics. [doi: 10.1063/1.3520572]“
“The O-antigen is a part of the lipopolysaccharide molecule present in the outer membrane of Gram-negative bacteria, and is essential for the full function of the microorganisms. Salmonella enterica and Escherichia coli are taxonomically closely related species. In this study, the O-antigen structures of S. enterica O16 and O38 and E. coli O11 were determined. Salmonella enterica O38 and E. coli O21 were found to have identical O-antigen structures, whereas S. enterica O16 and E. coli O11 had closely related structures, differing only in the presence of a lateral glucose residue and O-acetylation of a mannose residue in the former.