In this study, on comparison of the two new techniques, scleroligation (Group III) versus band ligation plus argon plasma photo coagulation (Group IV), we found that the required sessions

for eradication of esophageal varices was lower in the scleroligation group, the complications that occurred during the follow up were more or less similar, and no significant statistical difference was found in variceal recurrence after obliteration between the two groups (F.X = 0.05). Thus, these new techniques are safe and effective. We can use either of these techniques according to the available equipment in the endoscopy unit. At present, equipment for argon plasma coagulation is not commonly Cell Cycle inhibitor available in every endoscopic unit, and

moreover, see more the cost–benefit correlation may favor the scleroligation method in the treatment protocol of portal hypertensive patients with bleeding varices, especially in poor and developing countries. Sclerotherapy is quite effective in achieving control of variceal bleeding and eradication of varices. It has an acceptable variceal recurrence rate and is not associated with major complications. The total costs are low but this therapy requires more sessions to obtain complete eradication, Etomidate and to some degree is the most painful technique. Band ligation allows rapid eradication of varices, but it was found to

be associated with the highest variceal recurrence rate. It is an easy technique, and requires fewer therapeutic sessions than sclerotherapy. It is less painful but more expensive in comparison to sclerotherapy. Scleroligation allows for very rapid eradication of varices, and avoids the disadvantage of band ligation alone. The recurrence rate following scleroligation was just 2%. The technique does not require special skills or equipment other than those needed for sclerotherapy or band ligation, however the total cost is higher than that of sclerotherapy. Band ligation plus argon plasma coagulation: As a method of post-endoscopic variceal ligation mucosal fibrosis therapy, APC achieved a better outcome than ligation alone. It is an excellent new treatment modality with a low variceal recurrence rate (4%), and no obvious recorded complications. However it is the most expensive technique and requires special equipment that is only available in a few endoscopic centers. “
“Aphthous stomatitis is one of the adverse effects associated with interferon (IFN) that forces dose reduction of IFN and there is no established therapy.