Participants who meet our pragmatic inclusion criteria and who sc

Participants who meet our pragmatic inclusion criteria and who score 20 or above on the MFQ will be consented into the trial and will be asked to provide demographic information and complete: The short Beck Depression Inventory (BDI) The MFQ The Spence Children’s Anxiety Scale (SCAS)

A risk Linifanib clinical trial factor schedule A Quality of Life and Resource Use questionnaire Consented participants will then be randomised to either Arm 1 or Arm 2. Intervention Arm 1: CCBT using the program ‘Stressbusters’ Stressbusters is a CCBT package developed by a team from Manchester, The Institute of Psychiatry, London and Australia (combining expertise in CBT and computer-based delivery). The Stressbusters software application consists of eight 30–45 min sessions of CCBT designed for 12–18 year olds. The programme is based on the manualised treatment programme from an RCT designed to evaluate effectiveness of CBT compared to a placebo control.21 Each Stressbusters

session is an interactive presentation featuring narration synchronised with videos, animations, graphics and printouts. The programme has a narrator guiding participants through eight sessions in linear progression, with each building on the knowledge gained in previous sessions and on the tasks carried out at home. A session or part of a session can be repeated wherever necessary. Sessions contain flexible ‘add-ons’ such as written fact sheets (eg, about bullying, sleep problems) which can be printed out and taken away, together with home practice related handouts from the programme (eg, mood diary sheets). The video inserts (case vignettes) are of three teenagers who feature throughout. They are student

actors who play the roles of depressed teenagers, specially scripted and created for the project. Participants hear about the lives of the teenagers and watch them using the programme in a combination of short video sequences and voiceovers. The session content is organised into the following format: Session 1: Introduction to the programme and goal setting Session 2: Getting activated Session 3: Emotional recognition Session 4: Noticing thoughts Session 5: Thought challenging Session 6: Problem solving Session 7: Improving social skills Session 8: Relapse prevention Dacomitinib Arm 2: websites This involves equivalent time to access selected websites chosen by an expert clinical panel containing general safe and official information on low mood/depression and self-help. The selected websites are: All participants will also be asked to complete the MFQ and BDI questionnaires at 4 months and 1 year after completion of/withdrawal from trial sessions. We will test the feasibility of using a likert scale to explore treatment preference as this could be used as a measure in a fully powered trial.

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