SETTING: Vissum-Instituto Oftalmologico de Alicante, Alicante, Spain.
METHODS: This prospective nonrandomized study comprised patients with visually significant cataract and moderate to high astigmatism (>2.00 diopters [D]). After MICS, an Acri.Comfort 646 TLC toric IOL was implanted in the selleck screening library capsular bag. The uncorrected (UDVA) and corrected (CDVA) distance visual acuities, residual refractive sphere,
residual refractive and keratometric cylinders, and IOL axis alignment were measured after 3 months. Vector analysis of astigmatism was by the Alpins method.
RESULTS: The study included 21 eyes (12 patients). The UDVA was 20/40 or better in 16 eyes (76.1%), and the CDVA was 20/30 or better in 18 eyes (85.7%). The mean refractive cylinder decreased significantly after surgery, from -4.46 D +/- 2.23 (SD) to -0.45 +/- 0.63 D (P<.05). Astigmatism analysis by vectors showed a mean surgically induced astigmatism vector of 0.99 x 1 degrees and a mean difference vector of 0.23
x 8 degrees. The mean index of success was 0.11 +/- 0.15. Ninety-one percent of astigmatism was corrected. The mean IOL axis rotation was -1.75 +/- 2.93 degrees; the rotation was 10 degrees or less in all eyes. No complications occurred.
CONCLUSION: Implantation of a toric IOL after MICS was a safe, precise, and effective procedure to correct moderate to high astigmatism in cataract patients.”
“Study Design. An in vitro study of simulated whiplash BYL719 mw using a hybrid cadaveric/surrogate model.
Objective. The goal of the
present study was to determine the effect of the active head restraint (AHR) on residual neck instability due to simulated rear impacts of a human model of the neck.
Summary of Background Data. Previous studies have indicated potential LY2835219 benefits of active injury prevention systems in reducing neck injuries during rear impacts.
Methods. Six osteoligamentous whole cervical spine specimens (occiput-T1) were prepared with vertebral motion tracking flags. The model, consisting of the neck specimen mounted to the torso of BioRID II and carrying an anthropometric surrogate head, was rear impacted (7.1 and 11.1 g) with and without the AHR. Pre- and post-impact flexibility tests identified significant residual instability (P < 0.05) above physiologic values and among experimental conditions. Linear regression analyses were used to identify correlation between spinal rotation peaks measured during impact and the resulting flexibility parameter increases (R(2) > 0.35 and P < 0.001).
Results. Our results indicated significant increases in the average flexibility parameters, up to 3.1 degrees, at C2-C3, C3-C4, and C5-C6 due to 7.1 g rear impacts even in the presence of the AHR. Subsequently, increases in the flexibility parameters progressed and spread to head/C1 and to the inferior spinal levels following the 11.1 g impacts.