Typical radiological

Typical radiological selleck inhibitor findings (Figure 2) were demonstrated by computed tomography (all patients) and by magnetic resonance imaging (MRI; eight of nine patients, 89%). Two patients (22%) suffered from multiple lesions, whereas the rest had a single lesion. In addition to the typical radiological findings, the diagnosis was supported by serology in four of nine patients. One patient was diagnosed following brain biopsy.

Data regarding treatment were available for seven patients: two patients refused antihelminthic therapy and five received standard albendazole therapy; one of them received three courses of albendazole treatment due to suspected appearance of a new lesion on MRI following treatment. All received adjunctive steroid treatment during antihelminthic therapy. All patients received antiepileptic therapy. Median duration of antiepileptic treatment was 16 ± 41 months after albendazole was given (range 1–120 mo). All patients were seizure free following discontinuation of antiepileptic therapy [average

seizure free follow-up period of 27 ± 25 months (range 3–60 mo)]. Radiologic follow-up data were available for eight patients. All of them had significant improvement; two of them had complete resolution of all radiological findings (Table 2). Complete resolution occurred in patients treated with albendazole. Radiologic improvement was documented in the two patients who refused treatment, however, this was partial improvement without complete resolution. During the study period, the PF-562271 datasheet estimated number of travel episodes of Israeli travelers to endemic countries was 2,400,000.9 Thus the estimated incidence of NCC among Israeli travelers is 1 : 275,000 per travel

episode to endemic region. (-)-p-Bromotetramisole Oxalate NCC has become an increasingly important cause of new onset seizures in developed countries.4 However, a majority of cases are still reported among immigrant populations from endemic areas, and infrequently related to travel. This report emphasizes the importance of considering NCC in the differential diagnosis of new onset seizures in developed countries, especially when epidemiologic data such as previous travel to endemic countries and radiologic features support this diagnosis. Human cysticercosis occurs following the ingestion of T. solium ova excreted in the feces of a person infected with the adult tapeworm, frequently by fecal–oral contamination (Figure 1b); either auto or heteroinfection may occur.11 As with other diseases transmitted by the fecal–oral route, all individuals in contact with a T. solium carrier may be at risk. Pork eating is thus not a necessary risk factor for the acquisition of NCC, as was demonstrated in a Jewish orthodox community in New York,12 and even strict vegetarians may be potential victims of the disease. Since fecal–oral transmitted diseases are very common among travelers, we would expect NCC to be prevalent in this population.

Leave a Reply

Your email address will not be published. Required fields are marked *

*

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>