We present the clinicopathological and immunohistochemical features of 7 cases of intraoral MC in attempt to better understanding this entity.

Study design. Seven intraoral MCs were retrieved from the files of the Department of Oral Pathology, School of Stomatology, Wuhan University, during a 10-year period. Immunohistochemical markers, including cytokeratin

(CK) AE1/AE3, S100, vimentin, smooth muscle actin (SMA), p63, and maspin, were used to further characterize these lesions. A review of contemporary relevant literature is also provided.

Results. The patients were 5 women and 2 men, and the age range was 37 to 75 years (mean 57.9 years). selleckchem Three cases arose in the hard palate, 2 in the retromolar region, and 1 each in the tongue and the floor of the mouth. Histologically, the tumors exhibited a solid architecture with cells arranged in nodules, nests, trabeculae, or cords. The epithelioid cell type is the most frequently encountered, followed by clear cells. The tumor-associated matrix is more prevalent hyalinized than myxoid. Immunohistochemically, CK AE1/AE3, S100, vimentin, p63, and maspin were expressed in all cases. Positivity for

SMA was seen in 3 tumors. Five patients with follow-up information CA-4948 cost showed no evidence of disease after a mean follow-up of 69.6 months (range 22-108 months).

Conclusions. Combining the current series with 21 additional cases in the literature indicated that myoepithelial carcinoma of intraoral minor salivary glands is generally a low-grade malignant tumor with little propensity for regional or distant metastasis and low recurrence. Awareness of the clinicopathological and immunohistochemical features of intraoral MC is necessary for accurate diagnosis. Wide local excision with tumor-free margins is the treatment of choice. (Oral Surg Oral

Med Oral Pathol Oral Radiol Endod 2010;110:85-93)”
“Equiatomic MnAu clusters with average sizes of 4 and 10 nm are produced by inert-gas condensation. As-produced clusters are used to form both dense cluster films and films with clusters embedded in a W matrix with a cluster volume fraction of 25%. Both structure and magnetism are size-dependent. Structural analysis of the 10 nm clusters indicate a distorted tetragonal body-centered Alisertib mouse cubic structure with lattice parameters a = 0.315 and c = 0.329 nm. The 4 nm clusters have a partially ordered tetragonal L1(0) structure with lattice parameters a = 0.410 nm and c = 0.395 nm. Magnetic properties of the clusters show evidence at low temperatures of mixed ferromagnetic and antiferromagnetic interactions and ordering as well as paramagnetic spins. Saturation moments are as large as 0.54 mu(B) per average Mn atom. The results are compared with earlier theoretical calculations on bulk MnAu. (C) 2011 American Institute of Physics. [doi:10.1063/1.3559502]“
“Objective. The objective of this study was to evaluate cone-beam CT (CBCT) diagnoses of sialoliths in the major salivary glands.

Study design.