When the loading speed is higher than the critical value, with the increase of speed, the maximum load increases rapidly; simultaneously, the critical indentation depth decreases rapidly. However, when the loading speed is lower than the critical value, the changes of F max and d c are not that obvious. When the loading speed decreases from 1.00 to 0.50 Å/ps, dropping by 50%, the value of d c increases by 33.35%, and the value of F max decreases by 8.43% correspondingly. Nevertheless, when the #www.selleckchem.com/products/Dasatinib.html randurls[1|1|,|CHEM1|]# loading speed decreases from 0.20 to 0.10 Å/ps, dropping by 50%, the changes of F max and d c are only 1.68% and 0.21%, respectively. The results may be attributed to the fact that

the higher the loading speed of the indenter, the less time it takes to go through the graphene sheet, resulting in a higher load and lower indentation depth than those at a lower loading speed, in which situation learn more the load process is much slower. Secondarily, the spherical indenter’s influences on results are observed by changing the indenter radius. The simulations of various indenter radii (1, 2, and 3 nm) are carried out at the speed of 0.20 Å/ps. The results of the load–displacement curve are shown in Figure  6b. The stress is more uniform in the middle of the graphene, so the F max increases obviously and the critical indentation

depth also becomes greater with the increase of the indenter radius. Finally, after changing the aspect ratio of the graphene film to 1.1 and 1.5, Young’s modulus and 3-mercaptopyruvate sulfurtransferase the maximum stress of the graphene are obtained using the methods mentioned above. It can be deduced from Figure  7 that Young’s modulus

and the maximum stress are the inherent properties of graphene and irrelevant to its size, which also verifies the formula obtained above. Figure 6 Comparison of load versus indentation depth for different parameters. (a) The indenter is loaded at different loading speeds between 0.10 and 2 Å/ps. (b) The indenter is loaded with different indenter radii of 1, 2, and 3 nm. Figure 7 Comparison of Young’s modulus and maximum stress versus the aspect ratio of the graphene film. Conclusions Some MD simulations of nanoindentation experiments on single-layer rectangular graphene sheets have been carried out in order to obtain the mechanical properties of graphene. A correlation between the load and the indentation depth is constructed, and Young’s modulus and the strength of graphene are obtained in the end. The simulation results show that the unloaded graphene film could make a complete recovery if the maximum indentation depth is less than the critical indentation depth, and the graphene film undergoes elastic deformation during the whole loading-unloading-reloading process. However, if the maximum indentation depth is larger than the critical indentation depth, the graphene sheet could not restore its original structures after unloading and the graphene deforms plastically.