As a result, these patients will most likely need surgical treatment and afterwards need a variable MI-503 clinical trial period of rehabilitation either in the convalescent hospital or in the community. This constitutes a significant health problem and a major burden to the society. In the past few decades, there have been advancements in the surgical implants in the treatment of fragility fractures. Modern methods of hip arthroplasty can provide a painless and highly functional outcome in the active elderly patients having femoral neck

fractures [5]. The sliding hip screw and intramedullary nailing using the same principles have been the standard treatment of intertrochanteric fractures [6]. Recently, an improvement in the fixation of the osteoporotic femoral head in the form of a helical blade has shed new light in related implant design CAL-101 nmr [7]. In addition to devising new implants and fixation materials, recommendations on the surgical technique and implant position such as the tip–apex distance of the lag screw position have also been established to help surgeons deliver the best surgery to their patients [8]. From a logical point of view, orthopedic surgeons hypothesize that by having the latest implant and performing

a successful surgery, they can have an immediate impact in the outcome of these patients. This goal has not been fully realized. Surgeons gradually realize that other factors may have equally significant influences on patient outcome. Instead of concentrating solely on pursuing excellence in surgical techniques to fix a fracture more stably, should we also put a big effort to improve the performance of existing medical care for such patients? Are these hip fracture surgeries done promptly without delay as in the case of other long bone fractures? Are the surgeries left in the hands of residents

who are relatively inexperienced? How about the other medical illnesses of these patients that may alter significantly the eventual outcome? In many parts of the world, a system of orthopedic trauma service and the organization of the hospital that values prompt treatment of these patients are lacking. Hence, the orthopedic surgeon encounters obstacles Cediranib (AZD2171) in delivering a prompt and effective surgical treatment to these patients. There are two main aspects in accounting for such delays to surgery. Hip fracture patients are typically in their 70s–90s. Pre-existing comorbidities are commonplace, and hence, many patients are not in the most Ralimetinib optimal body conditions to undergo anesthesia and surgical procedures. To correct the underlying medical conditions will often need some time. To address this situation, an individual assessment is required upon hospital admission, and individualized therapy programs should be planned. This assessment must be completed as soon as possible to allow the patient’s condition to be rapidly optimized for surgery.