We have found that lateral interaction of the LS-SS is much stronger than the longitudinal one, and it is mainly mediated by hydrophobic interactions. This study will not only enhance our understanding of the interaction between the SS and the LS of AGPase, but will also enable us to engineer proteins to
obtain better assembled variants of AGPase which can be used for the improvement of plant yield.”
“Abiotic stress caused by global climate change varies widely, which negatively affect crops growth and productivity throughout the world. Environmental changes can alter plant’s physiological state and trigger Crenigacestat several signaling pathways for adaptation to unfavorable conditions. Plant response to abiotic stress includes changes in protein expression and post-translational modification of proteins to activate their defense system against the challenges. Research on plant proteomes has provided beneficial information for a comprehensive understanding of the protein networks in plants in response to external
stimuli. Large-scale proteomics is a powerful approach for studies of complex biological processes in which a number of proteins take part; proteome analysis of sub-cellular structures and modified proteins has enabled identification of novel components of plant stress responses that had not previously been discovered. In this review, we have discussed the recent developments of crop proteomics in the context Adavosertib concentration of several climatic factors including photosynthetic stress, air pollutants, thermal stress including heat and cold, and osmotic stress, RG-7388 including drought, salt, and flooding stress, and metal stress. The aim of this review is to take a snapshot of several proteomic approaches in crop plants that provide a comprehensive
list of components affected by certain abiotic stresses in climate. The biological relevance of these proteins in regard to plant stress tolerance will be described as well. (c) 2009 Elsevier Ltd. All rights reserved.”
“Diabetes and osteoporosis are common and complex disorders with an enormous health burden that can be often associated especially in middle-age and elderly individuals. Although there is raising awareness of the higher fractures rates among patients with type 1 (DM1) and 2 (DM2) diabetes, there are few data available on the pathogenetic mechanisms responsible for this increased risk. Importantly, several experimental and clinical observations suggest that bone abnormalities associated with diabetes may differ, at least in part, from those associated with senile or post-menopausal osteoporosis. This implies that specific preventive and therapeutic strategies have to be developed and tested to prevent fractures in DM1 and DM2 patients. It is also likely that shared (i.e. due to glucose-toxicity) as well as different (i.e.